GABOPEN NT is a combination medicine containing Gabapentin & Nortriptyline, used for the effective management of neuropathic pain—a chronic nerve condition caused by damage or dysfunction in the nervous system. This type of pain is often described as burning, stabbing, shooting, or electric shock-like sensations, and may occur without any physical trigger or due to normally non-painful stimuli.

Gabapentin, an anti-convulsant, works by binding to specific sites on voltage-gated calcium channels in the central nervous system, thereby modulating the transmission of pain signals and reducing nerve excitability. Nortriptyline, a tricyclic antidepressant, prevents the reuptake of neurotransmitters serotonin and noradrenaline, enhancing their pain-inhibiting effects in the brain. Together, these agents provide both central and peripheral pain relief, improving sleep quality, reducing nerve sensitivity, and helping patients manage chronic neuropathic conditions more comfortably.